Other Clinical Trial - Analysis of Biomarkers for Acute NCT01569373

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Clinical Trial Details — Status: Withdrawn

Samples of blood and urine will be analyzed for biomarkers to check their predictivity of Graft-versus-Host Disease (GVHD) outcomes.

To determine if serum biomarkers of inflammation correlate with onset and severity of acute GVHD, particularly GVHD of the gut.

Recruitment information / eligibility
Status	Withdrawn
Enrollment	0
Est. completion date	October 2017
Est. primary completion date	October 2017
Accepts healthy volunteers	No
Gender	All
Age group	18 Years and older
Eligibility	Inclusion Criteria: - 18 years old or older patients - Undergoing allogeneic stem cell transplant Exclusion Criteria: None

Locations
Country	Name	City	State
United States	Mayo Clinic	Rochester	Minnesota

Sponsors *(1)*
Lead Sponsor	Collaborator
Mayo Clinic

United States,

Outcome
Type	Measure	Description	Time frame	Safety issue
Primary	Diagnosis of severe acute GVHD		2 months

See also
Status	Clinical Trial	Phase
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Completed	`NCT01010217` - Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide	Phase 2
Completed	`NCT02997813` - Assessment of Mobilization Cost for Multiple Myeloma Using 2 Different Mobilization Strategies	N/A
Terminated	`NCT01135355` - Cytokine Assay for Early Identification of Pediatric Stem Cell Transplant Recipients
Completed	`NCT01174277` - Pilot Study: Patients With Chronic Active Graft Versus Host Disease That Have Failed or Not Tolerated Standard Therapy.	Phase 0
Active, not recruiting	`NCT04473911` - Haplo Peripheral Blood Sct In GVHD Prevention	Phase 1
Terminated	`NCT00667784` - Long Term Minor Sibling Donor Well-Being	N/A