Chronic Renal Failure/ Kidney Disease Clinical Trial
Official title:
Randomized Controlled Study for Evaluation of the Impact of Red Wine, White Wine and Beer Intake on Contrast-Medium Induced Acute Kidney Injury
Patients with impaired renal function are at elevated risk for development of
contrast-medium induced acute kidney injury (CI-AKI). CI-AKI is associated with increased
risk for cardiovascular morbidity and mortality. Effective CI-AKI prevention strategies are
needed.
The RenPro-II-WINE Trial was designed to test the hypothesis whether moderate red wine
consumption prior to contrast-medium use is effective in CI-AKI prevention.
Consecutive patients with impaired renal function undergoing elective coronary angiography
will be assigned in one of four treatment arms: a. control patients receiving standard care
b. patients receiving standard care plus red wine c. patients receiving standard care plus
white wine d. patients receiving standard care plus beer This study will give important
answers on how to prevent CI-AKI in patients with impaired renal function undergoing
contrast media exposure.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention