Combined Inflammatory and Immunologic Defect Clinical Trial
Official title:
Perioperative Evaluation of Immuno-inflammatory Parameters
This study consists of evaluations, using blood tests, various immune, inflammatory and
coagulation parameters in the perioperative settings (different substudies), without
changing anything to what is expected.
This will allow us to clarify the possible impact of surgery and analgesia on perioperative
activation of these pathways.
A significant number of published data can be concluded that surgery and anesthetic and
analgesic techniques have an impact on immunity and inflammation.
However, none of these studies have been performed with modern techniques, much more
reliable evaluation of immune activity, such as the assessment of monocytic degranulation by
flow cytometry.
It is therefore important to document immune activity using these new techniques, our
patients, perioperative. This will be analyzed, so observational, the potential impact of
different therapeutic interventions the patient receives.
This study consists of evaluations, using blood tests, various immune, inflammatory and
coagulation parameters in the perioperative settings (different substudies), without
changing anything to what is expected.
This will allow us to clarify the possible impact of surgery and analgesia on perioperative
activation of these pathways.
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