Humoral and Cellular Immune Responses Clinical Trial
Official title:
Characterisation of Cellular and Humoral Immunity in Elderly People After Immunization With a Purified, Inactivated Japanese Encephalitis Vaccine.
| Verified date | March 2018 |
| Source | Medical University of Vienna |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
The aim of this project is to investigate humoral and cellular immune responses before and after immunisation with the Japanese encephalitis vaccine IXIARO in subjects above 60 years of age and 18-40 years old subjects.
| Status | Completed |
| Enrollment | 60 |
| Est. completion date | November 2013 |
| Est. primary completion date | October 2012 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 18 Years to 99 Years |
| Eligibility |
Inclusion Criteria: - adults (18-40 years old) - adults (=60 years), - both sexes - willingness to sign written informed consent form Exclusion Criteria: - age below 18 years or between 41-59 years old - status post japanese encephalitis, tick born encephalitis (TBE), dengue, yellow fever or West Nile virus infection - previous immunization against yellow fever, japanese encephalitis (dengue or WNV) - current acute infection (body temperature above 37,9°C) |
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| Medical University of Vienna |
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | cellular immunity (cytokine production upon stimulation with Japanese Encephalitis (JE) Virus Antigen) 7 days after the 2. JE-vaccination | 7 days after the 2 JE vaccinations |