Lymphoma in the Orbit

Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma Clinical Trial

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT01302912
• Other study ID #: USZ-OALs-Register
• Status: Enrolling by invitation
• Phase: Phase 4
• First received: February 23, 2011
• Last updated: November 3, 2011
• Start date: February 2011
• Est. completion date: May 2012

Study information

• Verified date: November 2011
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: UZurich
• Study type: Observational

Clinical Trial Summary

Imaging techniques have considerably improved over the last decades and ocular adnexal lymphomas (OALs) nowadays can be detected. As major advances in immunophenotyping and molecular diagnostics in histology have been achieved offering an accurate diagnosis, the investigators would like to introduce that surgical biopsy of an orbital lymphoma becomes crucial for the possibility of a correct diagnosis and proper treatment. As radiotherapy accomplished great preciseness as well and OALs respond excellently to radiation, this therapy should be the treatment of choice in local defined lymphomas instead of blind treatment with steroids. Radiation results in great local control rates of 85% to 100%

• Trial with surgical intervention

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 50
• Est. completion date: May 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion criteria: - both genders

• >17 years of age

• underwent biopsy of an ocular adnexal lymphoma between 01/2006 and 12/2010 at the University Hospital Zurich, Division of Ophthalmology

• diagnosis histologically proven

Exclusion criteria:

• less than 18 years of age

• patient underwent no MRI before surgery (biopsy)

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Lymphoma, B-Cell, Marginal Zone
• Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma

Intervention

Procedure:
• Lymphoma-Biopsy
Patients after biopsy of orbital lymphoma

Locations

Country	Name	City	State
Switzerland	University Hospital Zurich, Ophthalmic Clinic	Zurich	ZH

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland,