Impact of Genetic Polymorphisms on Dental Implant Loss

Patients Treated by Means of 1 or More Dental Implants Clinical Trial

— Polymorphism  

Official title:

A Case-control Study on the Impact of Genetic Polymorphisms on Dental Implant Loss.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01274442
• Other study ID #: 2010/771
• Status: Completed
• Phase: N/A
• Start date: June 1, 2011
• Est. completion date: August 5, 2013

Study information

• Verified date: December 2022
• Source: University Hospital, Ghent
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Patients that may participate in this case-control study underwent dental implant surgery in the University Hospital in Ghent in 2004-2007.

According to one of our recent papers based on this patient group, 34/461 patients lost one or more implants. The goal is to invite these 34 patients, to update the anamnesis, to perform a brief clinical oral examination and to have a blood sample. The latter is necessary to identify relevant genetic polymorphisms of the patient that are associated with implant loss. Among the remaining patients that did not lose implants, another 34 'controls' will be invited for the same examinations.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 13
• Est. completion date: August 5, 2013
• Est. primary completion date: August 5, 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Dental implant surgery in the University Hospital in Ghent in 2004-2007.

• Case: dental implant loss

• Control: no dental implant loss

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Patients Treated by Means of 1 or More Dental Implants

Intervention

Other:
• anamnesis
To update the anamnesis.

Procedure:
• oral examination
A brief clinical oral examination will be performed.
• Blood sample
A blood sample will be taken to identify relevant genetic polymorphisms.

Locations

Country	Name	City	State
Belgium	University Hospital Ghent	Ghent

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Ghent

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	genetic polymorphisms associated with implant loss	Identification of genetic polymorphisms that are associated with implant loss. It concerns only one evaluation (1 blood sample).	after 3 to 6 years

External Links

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