Resistance Exercise in Healthy Men

Single Bout of Resistance Type Exercise Clinical Trial

Official title:

The Effect of Age and Dietary Protein Intake on Myocellular Characteristics Following a Single Bout of Resistance Exercise in Healthy Men

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01220037
• Other study ID #: MEC 09-3-080
• Status: Completed
• Phase: N/A
• First received: October 7, 2010
• Last updated: October 25, 2013
• Start date: April 2010
• Est. completion date: December 2011

Study information

• Verified date: October 2013
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
• Study type: Interventional

Clinical Trial Summary

In the present study, the effects of age and dietary intake will be assessed on myocellular characteristics during 72 hours after a resistance type exercise session.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: December 2011
• Est. primary completion date: September 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• healthy men between the ages of 18-30 or 70-85 years

Exclusion Criteria:

• Subjects with a recent history or current state of cardiovascular disease, COPD, Parkinson, rheumatoid arthritis, musculoskeletal/orthopaedic disorders, renal disorder, cognitive impairment.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Single Bout of Resistance Type Exercise
• Standardized Diet

Intervention

Behavioral:
• Adhere to a specific standardized diet for 4 days
24 h before the start of the intervention all subjects will adhere to a standardized diet for 4 days. Young subjects are randomly allocated to either a low protein diet, regular protein diet or high protein diet group. All elderly subjects will adhere to a regular protein diet comparable to the regular protein diet of the young subjects.

Locations

Country	Name	City	State
Netherlands	Maastricht University Medical Centre	Maastricht	Zuid Limburg

Sponsors (1)

Lead Sponsor	Collaborator
Maastricht University Medical Center

Country where clinical trial is conducted

Netherlands, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle fiber myonuclear and stem cell content		baseline	No
Primary	Muscle fiber myonuclear and stem cell content		12 hours after a single bout of resistance type exercise	No
Primary	Muscle fiber myonuclear and stem cell content		24 hours after a single bout of resistance type exercise	No
Primary	Muscle fiber myonuclear and stem cell content		48 hours after a single bout of resistance type exercise	No
Primary	Muscle fiber myonuclear and stem cell content		72 hours after a single bout resistance type exercise	No