Non Previously Treated CD20+ Diffuse Large B-cell Lymphoma Clinical Trial
Official title:
PHASE II STUDY OF MINI-CHOP PLUS OFATUMUMAB (O) IN NON PREVIOUSLY TREATED PATIENTS AGED OVER 80 YEARS WITH CD 20+ DIFFUSE LARGE B-CELL LYMPHOMA
This study is a multicentric, phase II, open-label, non-randomized trial evaluating the
efficacy of O-miniCHOP in patients aged over 80 years with non previously treated CD20+
diffuse large B-cell lymphoma (age-adjusted IPI=0 to3), stage I, II, III or IV with a
performance status ECOG from 0 to 4.
The anticipated study dates (start / end) are: 2010 - 2013. The study will evaluate a cohort
of 120 patients (approximately 95 in France, 15 in Belgium, 5 in Switzerland and 5 in
Portugal).
Patients will be recruited over 30 months and followed at least one year after the last
patient has been included.
The duration of the treatment period is approximately 20 weeks.
n/a