Secondary or Tertiary Peritonitis Clinical Trial
Official title:
Etude Prospective Sur l'Impact de l'Utilisation de la Procalcitonine Dans l'évaluation de la Poursuite ou de l'arrêt du Traitement Antibiotique Empirique Lors de péritonites et d'Infections Intra-abdominales
| Verified date | December 2014 |
| Source | University of Lausanne Hospitals |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Switzerland: Ethikkommission |
| Study type | Observational |
Procalcitonin level used for determining length of antibiotic treatment in peritonitis and intra-abdominal infections. Hypothesis is that length of antibiotic use can be shortened by this method.
| Status | Completed |
| Enrollment | 162 |
| Est. completion date | June 2014 |
| Est. primary completion date | June 2014 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - More than 18 yo - Patient requiring surgery for peritonitis or intra-abdominal infection following: perforation, necrosis, previous operation... - Mannheim Peritonitis score > 14 - SIRS present - Probability of survival > 72h - Informed consent by patient/relatives Exclusion Criteria: - No SIRS - Long date corticoid treatment - Immunosuppression - Thyroid medullary carcinoma - Anaphylactic shock - Acute hepatic deficiency |
Observational Model: Cohort, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Switzerland | University Hospital of Lausanne | Lausanne |
| Lead Sponsor | Collaborator |
|---|---|
| University of Lausanne Hospitals |
Switzerland,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | antibiotic treatment length, hospitalisation length without antibiotic, infection recurrence, antibiotic cost | at one month and during hospital stay | Yes |