Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to evaluate the safety and tolerability of NMS-1286937, a polo-like-kinase 1 inhibitor, in patients with advanced metastatic solid tumor.


Clinical Trial Description

n/a


Study Design

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms

  • Advanced or Metastatic Solid Tumors

NCT number NCT01014429
Study type Interventional
Source Nerviano Medical Sciences
Contact
Status Completed
Phase Phase 1
Start date November 2009

See also
  Status Clinical Trial Phase
Active, not recruiting NCT05017012 - A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of MK-3475A (Pembrolizumab Formulated With MK-5180) In Advanced Solid Tumors (MK-3475A-C18) Phase 1
Completed NCT02261532 - A Phase I Study of TAS-102 in Solid Tumors Phase 1
Completed NCT00748553 - A Phase I/II Clinical Trial of Vidaza With Abraxane in the Treatment of Patients With Advanced or Metastatic Solid Tumors and Breast Cancer Phase 1/Phase 2
Completed NCT03248843 - A Study of PD-L1 Antibody KN035 in Japanese Subjects With Locally Advanced or Metastatic Solid Tumors Phase 1
Recruiting NCT05572684 - A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors Phase 1/Phase 2
Terminated NCT04003623 - Efficacy and Safety of Pemigatinib in Participants With Solid Tumors With FGFR Mutations or Translocations (FIGHT-208) Phase 2
Terminated NCT05496595 - DCBY02 as a Monotherapy in Patients With Advanced or Metastatic Solid Tumors Phase 1
Active, not recruiting NCT01928394 - A Study of Nivolumab by Itself or Nivolumab Combined With Ipilimumab in Patients With Advanced or Metastatic Solid Tumors Phase 1/Phase 2
Terminated NCT01506934 - A Study Evaluating the Bioavailability of Two Formulations of Linifanib and Food Effect on Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid Tumors Phase 1
Completed NCT03730337 - Phase 1 Study of ONO-7475 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors Phase 1
Recruiting NCT04586270 - A Study of TAS0612 in Participants With Advanced or Metastatic Solid Tumor Cancer Phase 1
Recruiting NCT06248411 - A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors Phase 1
Not yet recruiting NCT06389526 - A Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors Phase 1
Completed NCT03665285 - A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors Phase 1/Phase 2
Not yet recruiting NCT05957081 - Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309 Phase 1
Active, not recruiting NCT03316638 - A Study of a New Investigational Medicinal Product to Treat Patients With Advanced or Metastatic Solid Tumors Phase 1/Phase 2
Terminated NCT01355302 - E7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine Alone in Patients With Advanced or Metastatic Solid Tumors and Previously Untreated Gastric Cancer Phase 1/Phase 2
Not yet recruiting NCT06074497 - A Phase 1, First-in-Human of KGX101 to Patients With Advanced or Metastatic Solid Tumors Phase 1
Recruiting NCT06448364 - A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination Phase 1
Active, not recruiting NCT04866134 - A Study of ERAS-007 as Monotherapy or in Combination With ERAS-601 in Patients With Advanced or Metastatic Solid Tumors Phase 1/Phase 2