Unspecified Adult Solid Tumor, Protocol Specific Clinical Trial
Official title:
Study of Positron Emission Tomography With 18-fluorodeoxyglucose in Detecting Cancer in Patients With Idiopathic Venous Thromboembolism
RATIONALE: Diagnostic procedures, such as fludeoxyglucose F 18 positron emission tomography,
may help find and diagnose cancer. It is not yet known whether standard diagnostic
procedures are more effective when given with or without fludeoxyglucose F 18 positron
emission tomography in finding cancer.
PURPOSE: This randomized clinical trial is studying fludeoxyglucose F 18 positron emission
tomography given together with standard diagnostic procedures to see how well it works
compared with standard diagnostic procedures alone in finding cancer in patients with a
blood clot in a vein.
OBJECTIVES:
Primary
- Demonstrate the efficacy, in terms of increased numbers of cancer diagnoses, of PET-CT
with 18-FDG in patients with idiopathic venous thromboembolism.
Secondary
- Assess the risk of cancer detected at 1 year.
- Assess whether PET allows earlier detection of cancer.
- Evaluate survival.
OUTLINE: This is a multicenter study.
All patients undergo standard (clinical and biological) diagnostic tests for cancer.
Patients are randomized to 1 of 2 diagnostic arms.
- Arm I: Patients undergo diagnostic fludeoxyglucose F 18 PET in addition to standard
methods.
- Arm II: Patients only undergo standard diagnostic methods. Patients are followed up for
2 years.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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