Sleep Initiation and Maintenance Disorders Clinical Trial
Official title:
Light Treatment for Sleep/Wake Disturbances in Alzheimer's Disease
The aim of this study is to demonstrate the efficacy of timed exposure to bright light for the treatment of disturbed nighttime sleep and daytime wake in community-dwelling dementia patients and their caregivers, and to determine if there are genetic relationships between memory problems and sleep problems
1. Efficacy: Up to 4 weeks of morning bright light exposure will be more efficacious than
morning dim light in consolidating nighttime sleep as assessed by actigraphy.
2. Predictors of response: We expect the primary predictor of treatment response will be
initial MMSE score. Secondary predictors include baseline sleep/wake and circadian
parameters and age.
3. Effectiveness: Bright light treatment will be more effective than dim light in improving
quality of life.
4. An understanding of some of the genetic markers of memory and/or sleep problems.
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