Skin Imaging With Technologies in Development

Pigmented Skin Lesion of Uncertain Nature Clinical Trial

Official title:

Non-invasive Imaging Modalities for Assessment of Normal and Lesional Skin

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00764920
• Other study ID #: 20086307
• Status: Recruiting
• Start date: October 2008
• Est. completion date: December 2024

Study information

• Verified date: June 2023
• Source: University of California, Irvine
• Contact: Hanna Kim, MA
• Phone: 949-824-9265
• Email: hhkim3[@]uci.edu
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect information on normal and lesional skin. The researchers understand that the purpose of this study is not to evaluate any particular treatment and an investigation of a new therapeutic intervention would require an additional protocol. Skin conditions to be studied include vascular lesions, pigmentary disorders, inflammatory conditions and neoplasms.

Description:

Normal and lesional skin will be assessed by the following imaging modalities:

1. Laser Speckle Imaging can provide information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.

2. Optical Coherence Tomography and Optical Doppler Tomography can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.

3. Photon Migration Spectroscopy can provide information about the amount of blood, oxygen, fat and water is in a tissue.

4. Multi-Spectral Imaging can provide a 3 dimensional image of structures within the skin.

5. Multiphoton Microscopy can provide images of structures of the skin.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 750
• Est. completion date: December 2024
• Est. primary completion date: December 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 7 Years and older

Eligibility

Inclusion Criteria:

• adult male or female 7 and older; able to carry out study instructions

Exclusion Criteria:

• Younger than 7 years old

• pregnant woman

• breast feeding

Related Conditions & MeSH terms

• Pigmentation Disorders
• Pigmented Skin Lesion of Uncertain Nature

Intervention

Device:
• non-invasive imaging modalities for assessment of skin
skin imaging

Locations

Country	Name	City	State
United States	Beckman Laser Institute Medical clinic	Irvine	California

Sponsors (1)

Lead Sponsor	Collaborator
University of California, Irvine

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Collect information on normal and lesional skin	Develop non-invasive imaging modalities for assessment of skin.	up to 12 weeks