Clinical Trials Logo

Clinical Trial Summary

This study will compare the anti-tumor efficacy of apricoxib and erlotinib with placebo and erlotinib as measured by time to disease progression to test the hypothesis that down regulation of COX-2 and EGFR pathways in patients with up-regulated COX-2 expression in tumor will have a clinical benefit compared with erlotinib alone.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00652340
Study type Interventional
Source Tragara Pharmaceuticals, Inc.
Contact
Status Completed
Phase Phase 2
Start date April 2008
Completion date March 2012

See also
  Status Clinical Trial Phase
Active, not recruiting NCT04965090 - A Study of Amivantamab and Lazertinib in People With Non-Small Cell Lung Cancer (NSCLC) Phase 2
Terminated NCT00769600 - Phase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLC Phase 2
Recruiting NCT04878952 - Testing the Addition of Activity Monitoring With a Wearable Electronic Device to Improve Patient Care During Treatment for Lung Cancer N/A
Recruiting NCT05681780 - Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC Phase 1/Phase 2
Completed NCT01773109 - Etirinotecan Pegol (NKTR-102) in NSCLC Phase 2
Suspended NCT05617313 - Study of GT103 in Combination With Pembrolizumab in Refractory, Metastatic Non-Small Cell Lung Cancer Phase 2