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A Study to Assess the Safety & Interaction Between GW679769, Dexamethasone, & Ondansetron When Taken by Healthy Adults

Nausea and Vomiting, Chemotherapy-Induced Clinical Trial

Official title:
An Open-Label, Phase I Study to Assess the Pharmacokinetic Interaction Between Repeat Doses of Oral Casopitant and Intravenous and Oral Doses of Dexamethasone and Intravenous and Oral Doses of Ondansetron When Administered in Healthy Adult Subjects

Clinical Trial Summary

GW679769 may affect liver enzymes that metabolize dexamethasone and ondansetron. This study is designed to test the safety and the extent of the GW679769 affect on dexamethasone and ondansetron levels in humans.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Nausea and Vomiting, Chemotherapy-Induced
  • Vomiting
Clinical Trial Details
NCT number NCT00437229
Study type Interventional
Source GlaxoSmithKline
Contact
Status Completed
Phase Phase 1
Start date February 19, 2007
Completion date May 15, 2007
View Details
See also
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Completed NCT00405080 - A Study in Healthy Subjects to Assess How Dosing of Rifampin Affects What the Body Does to a Dose of GW679769 (Casopitant). Phase 1
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Completed NCT00601172 - A Study Of IV Casopitant For The Prevention Of Chemotherapy Induced Nausea And Vomiting. Phase 3
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Completed NCT00366834 - Intravenous And Oral Casopitant (GW679769) For The Prevention Of Chemotherapy Induced Nausea And Vomiting Phase 3
Completed NCT00104403 - Study Of Prevention of Chemo-Induced Nausea and Vomiting Caused By Moderately Emetogenic Chemotherapy Phase 2
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Completed NCT00460707 - A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults Phase 1