Is it Possible to Treat Cyanide Poisoning With HBO?

Carbon Monoxide Poisoning From Fire Accidents Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00399100
• Other study ID #: 01-277/99
• Status: Completed
• First received: November 13, 2006
• Last updated: March 19, 2018
• Start date: November 2006
• Est. completion date: November 2006

Study information

• Verified date: November 2006
• Source: Rigshospitalet, Denmark
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

People who has been in a fire accident have been shown often to be cyanide poisoned as well as poisoned with carbon monoxide(CO). According to recommendations from the Danish Health Agency people who are CO poisoned must be treated with hyperbaric oxygen (HBO). We want to see if HBO treatment can also treat cyanide poisoning.

The hypothesis is that as cyanide binds the same place in the mitochondria as CO cyanide will be detached from the mitochondria like CO and diffuse back to the blood.This way it will be easier to treat with hydroxycobalamin.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: November 2006
• Est. primary completion date: November 2006
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Going to receive HBO treatment for carbon monoxide poisoning from fire accidents

Exclusion Criteria:

• Under 18 years

Related Conditions & MeSH terms

• Carbon Monoxide Poisoning
• Carbon Monoxide Poisoning From Fire Accidents
• Poisoning

Intervention

Procedure:
• HBO - hyperbaric oxygen treatment

Locations

Country	Name	City	State
Denmark	Lab. for hyperbar medicin, afs. 4092, Anæstesi og Operationsklinikken, HOC, Rigshospitalet	København Ø

Sponsors (1)

Lead Sponsor	Collaborator
Rigshospitalet, Denmark

Country where clinical trial is conducted

Denmark,