Inflammation in Children With Attention-Deficit/Hyperactivity Disorder — ADHD_CYTO  

Attention-Deficit/Hyperactivity Disorder Clinical Trial

Official title: Inflammation in Children With Attention-Deficit/Hyperactivity Disorder

Status Not yet recruiting

Clinical Trial Summary

The aim of this study is to investigate the inflammatory response in children with this disorder.

Clinical Trial Description

Attention deficit-hyperactivity disorder (ADHD) is a prevalent childhood neuropsychiatric disorder, characterized by age-inappropriate and impairing levels of inattention, hyperactivity and impulsiveness. Approximately 5-10% of school-age children are affected by ADHD, and in many cases, symptoms persist into adolescence and adulthood.

Cytokines are key mediators of immune function and can be either pro-inflammatory or anti-inflammatory. Recently few studies have suggested involvement of cytokine pathways in subjects with ADHD.

Polymorphism of IL-1 receptors antagonists' alleles have been suggested in families and subjects suffering from ADHD. Moreover, a new variant of inflammatory bowel disease, another immunological based disease, was recently suggested in children with ADHD and other developmental disorders. There are no other published reports on cytokine production in children who suffer from ADHD. ;

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Attention Deficit Disorder with Hyperactivity
• Attention-Deficit/Hyperactivity Disorder
• Hyperkinesis

• NCT number: NCT00391495
• Study type: Observational
• Source: Tel-Aviv Sourasky Medical Center
• Contact: Nachum Vaisman, Prof. (MD)
• Phone: 972-3-6974807
• Email: vaisman@tasmc.health.gov.il
• Status: Not yet recruiting
• Phase: N/A
• Start date: September 2007
• Completion date: December 2007