Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields

Brain and Central Nervous System Tumors Clinical Trial

Official title:

Assessment of Occupational EMF Exposure - Validation of Interview Procedures Used in Brain Tumor Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00340054
• Other study ID #: 99906013
• Secondary ID: 06-C-N0139999060
• Status: Completed
• Phase: N/A
• First received: June 19, 2006
• Last updated: March 7, 2012
• Start date: October 2005
• Est. completion date: March 2007

Study information

• Verified date: March 2012
• Source: National Institutes of Health Clinical Center (CC)
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Observational

Clinical Trial Summary

RATIONALE: Electric and magnetic fields may increase the risk of cancer. Developing interview questions that accurately estimate a person's exposure to electric and magnetic fields may help doctors learn about the long-term effects of workplace exposure.

PURPOSE: This clinical trial is developing interview questions that can be used in estimating workplace exposure to electric and magnetic fields.

Description:

OBJECTIVES:

• Validate an interview-based electric and magnetic field exposure (EMF) assessment algorithm against measurements of the time-weighted average magnetic field magnitude used in previous epidemiologic studies.

• Calibrate the parameters in the algorithm in order to improve the exposure estimates.

• Correlate EMF exposure estimates from the algorithm with biologically based metrics measured by new instrumentation.

OUTLINE: Participants respond to questions during a 5- to 15-minute telephone interview concerning workplace exposure to electric and magnetic (EMF) fields. Data is collected during the interview using an exposure assessment algorithm designed to estimate EMF workplace exposure based on participants' responses. The interview-based estimates are then validated against actual field measurements of magnetic field exposure captured by Emdex multiwave monitors located at participating sites.

Other known NCT identifiers

• NCT00481910

Recruitment information / eligibility

• Status: Completed
• Enrollment: 108
• Est. completion date: March 2007
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

DISEASE CHARACTERISTICS:

• Meets 1 of the following occupation criteria:

• Three occupations that primarily work in offices at Lawrence Livermore National Laboratories (LLNL)

• Three occupations that do nonelectric manual work (e.g., machinists and laborers) at LLNL

PATIENT CHARACTERISTICS:

• Not specified

PRIOR CONCURRENT THERAPY:

• Not specified

Study Design

N/A

Related Conditions & MeSH terms

• Brain and Central Nervous System Tumors
• Central Nervous System Neoplasms
• Nervous System Neoplasms

Intervention

Other:
• questionnaire administration

Procedure:
• study of high risk factors

Locations

Country	Name	City	State
United States	National Institute for Occupational Safety and Health	Cincinnati	Ohio
United States	Exponent, Inc.	Menlo Park	California

Sponsors (2)

Lead Sponsor	Collaborator
National Institutes of Health Clinical Center (CC)	National Cancer Institute (NCI)

Country where clinical trial is conducted

United States, 

References & Publications (1)

Kelsh MA, Kheifets L, Smith R. The impact of work environment, utility, and sampling design on occupational magnetic field exposure summaries. AIHAJ. 2000 Mar-Apr;61(2):174-82. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Validation of an interview-based electric and magnetic field (EMF) exposure assessment algorithm
Primary	Calibration of algorithm parameters
Primary	Correlation between EMF exposure estimates from the algorithm with biologically based metrics measured by new instrumentation