Infants With Positive GBS Bacteremia Clinical Trial
Official title:
Clinical Outcome of Neonate With GBS Positive Culture-12 Year Retrospective Study
Streptococci group B (GBS) is a the major reason for morbidity and mortality in neonates. It
can present as pneumonia ,meningitis or sepsis.The mortality today is 5-20% and even more in
preterm babies.
During the past two decade, the introduction of protocols for prophylactic antibiotics for
women with a high risk for GBS infection, have led to a decline of 65% in GBS cases(0.32 for
1000 live birth compared to 1.8 cases in 1000).The purpose of the study is to check the
morbidity and mortality at Sheba medical center in the last 12 years in children with
positive blood culture for GBS. We assume that in our hospital the morbidity and mortality
is less then expected. If proven right, we would then check the reasons for that outcome
considering the type and length of treatment and the different virulence of the
streptococcus.
This is a retrospective case control study. We will review from archive the charts of all the neonates with positive blood culture for GBS, reviewing the course and severity of their illness. ;
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