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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00202475
Other study ID # PPO-C-02-15
Secondary ID
Status Completed
Phase Phase 3
First received September 13, 2005
Last updated October 19, 2009
Start date September 2003
Est. completion date December 2007

Study information

Verified date October 2009
Source Sanquin Research & Blood Bank Divisions
Contact n/a
Is FDA regulated No
Health authority Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
Study type Interventional

Clinical Trial Summary

The project will determine the advantages of double erythrocytapheresis in the collection of preoperative autologous erythrocytes as compared to the standard collections of whole blood. The study will assess the total reduction in the number of procedures required to obtain the preoperative units ordered by the surgeon. Also, successfulness of erythrocytaphereses versus classical whole blood collection for these patients will be compared.


Description:

The project will determine the advantages of double erythrocytapheresis in the collection of preoperative autologous erythrocytes as compared to the standard collections of whole blood. The study will assess the total reduction in the number of procedures required to obtain the preoperative units ordered by the surgeon. Also, successfulness of erythrocytaphereses versus classical whole blood collection for these patients will be compared.


Recruitment information / eligibility

Status Completed
Enrollment 100
Est. completion date December 2007
Est. primary completion date September 2006
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Elective surgery

Exclusion Criteria:

- Malignancies

- Severe arrhythmias

- Congestive heart failure

- Recent angina

- Epileptic seizures in the last 3 months before collection

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms

  • Pre Operative Autologous Donation

Intervention

Procedure:
eythrocytapheresis
machinal collection of erythrocytes
whole blood collection
collection of whole blood

Locations

Country Name City State
Netherlands Sanquin Blood Bank Southeast Region Maastricht
Netherlands Sanquin Bloodbank Maastricht Limburg

Sponsors (3)

Lead Sponsor Collaborator
Sanquin Research & Blood Bank Divisions Atrium Medical Center, Maasland Hospital

Country where clinical trial is conducted

Netherlands, 

Outcome

Type Measure Description Time frame Safety issue
Primary decline in Hemoglobine levels surgery Yes
Secondary Storage parameters- ATP 35 days No

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