Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer — CIRCULATE PAC  

Colon or Upper Rectum Adenocarcinoma Clinical Trial

Official title: Phase III Multicentric, Open-label, Randomized Study to Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer (PRODIGE 88)

Status Not yet recruiting

Clinical Trial Summary

Phase III multicentric, open-label, randomized study The main objective is to assess the efficacy on time to disease recurrence (TTR) of treating minimal residual disease diagnosed by the presence of ctDNA after full treatment (surgery + chemotherapy) in stage III or high-risk stage II colon or upper rectum adenocarcinoma

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Adenocarcinoma
• Colorectal Neoplasms

• NCT number: NCT06197425
• Study type: Interventional
• Source: Centre Hospitalier Universitaire Dijon
• Contact: Julien TAIEB
• Phone: 01 56 09 50 42
• Email: julien.taieb@egp.aphp.fr
• Status: Not yet recruiting
• Phase: Phase 3
• Start date: January 2024
• Completion date: January 2030