Clinical Trials Logo

Clinical Trial Summary

This study will assess global small molecule profiles identified in the human gastrointestinal tract of healthy human volunteers.


Clinical Trial Description

The gut is home to an extensive interaction between the host and its microbiota, in different regions exposed to endogenous and exogenous signals, such as nutrition, medications, immune alterations, and geographical location-related factors. this study aims to characterize the small molecule profiles of a cohort of healthy individuals, including their polar, semi-polar, non-polar, and protein landscape. The investigators will develop a pipeline enabling to integrate these small molecule profiles with a variety of inter-individual readouts, as assessed in stools of healthy volunteers. Data will be used to characterize molecular patterns potentially associated with a variety of dietary, immune, and health-related human features, with an aim to characterize small molecules for future causative investigation. ;


Study Design


NCT number NCT05951972
Study type Interventional
Source Weizmann Institute of Science
Contact Avner Leshem, MD
Phone +97289524014
Email avner.leshem@weizmann.ac.il
Status Recruiting
Phase N/A
Start date April 15, 2023
Completion date May 1, 2026