Clinical Trials Logo
  1. Home
  2. Other
  3. NCT05840926

Probiotic S. Salivarius K12 for the Prevention of Upper Respiratory Tract Infection in Nursery-age Children — PUNK  

Upper Respiratory Tract Infection Clinical Trial

Official title:
Possible Prophylactic Role of the S. Salivarius K12 Probiotic Strain for the Upper Respiratory Tract Infection and Nursery-age Children

Clinical Trial Summary

The purpose of this retrospective study is to assess the treatment benefits of probiotic Streptococcus salivarius K12 for the prevention of recurrent bacterial and viral infections of the pharynx, tonsils and ears in children under 3 years of age.

Clinical Trial Description

Recurrent bacterial and viral infections of the pharynx, tonsils and ears are a problem that can affect children of all ages. The persistence of these infections can lead to an overuse of drugs such as antibiotics, antipyretics and anti-inflammatories, with the possible consequent presence of side effects and above all an increase in antibiotic resistance, a global public health issue. In search at reducing the use of antibiotics and antivirals, there is currently a great scientific interest in probiotic therapies for the oral cavity infection. The aim of this retrospective, controlled, multicenter, non-profit study is to evaluate the efficacy and safety of the administration of Streptococcus salivarius K12 in pediatric patients attending the 1st or 2nd year of nursery school (< 3 years of age ), in the prophylaxis of the most common bacterial or viral respiratory infections, assessing the consequent reduction in the use of antibiotics, antivirals or other therapies compared to children. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05840926
Study type Interventional
Source Liaquat University of Medical & Health Sciences
Contact
Status Completed
Phase N/A
Start date January 5, 2022
Completion date March 31, 2023
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT06052540 - Probiotic Supplementation in Children Affected by Upper Respiratory Infections N/A
Completed NCT04960878 - The Effect of Synbiotics on the Upper Respiratory Tract Infection N/A
Terminated NCT00979667 - A Clinical Trial Comparing Oseltamivir With Placebo And Zanamivir With Control As First Line Treatment For Human Swine Influenza Infection Phase 3
Recruiting NCT04479657 - Qingfei Granule for the Treatment of the Pediatric Acute Upper Respiratory Tract Infection With Bacterial Infection Early Phase 1
Completed NCT04239521 - The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
Recruiting NCT06065176 - The Efficacy of the 2023-2024 Updated COVID-19 Vaccines Against COVID-19 Infection Phase 4
Recruiting NCT01985620 - The Impact of a Short Intervention During RSV Prophylaxis on Influenza Vaccination Rate. N/A
Completed NCT01875757 - Effect of Supplementation With Vitamin D on the Acute Bronchitis Prevention During the First Year of Life Phase 3
Recruiting NCT00551382 - Montelukast as Prophylaxis for Upper Respiratory Tract Infections in Children: a Randomised, Double-blind, Placebo-controlled Study Phase 3
Completed NCT00393835 - A Trial Of Azithromycin SR For The Treatment Of Laryngopharyngitis or Tonsillitis or Acute Bacterial Rhinosinusitis Phase 3
Not yet recruiting NCT05612893 - Discover the Immune Signature of Sepsis Caused by Acute Pulmonary Infection: A Cohort Study
Completed NCT06149117 - Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China Phase 4
Active, not recruiting NCT05569330 - Effect of Aerosol Filtering on Infectious Diseases in Day Care N/A
Recruiting NCT05374070 - Antiviral Activity of Oral Probiotics N/A
Completed NCT00707941 - Oseltamivir Randomised Controlled Efficacy Trial Phase 3
Completed NCT00858494 - Homeopathic Cold Medicine for Children N/A
Completed NCT04955327 - To Compare the Efficacy and Tolerability of A. Paniculata/A. Chilensis in Individuals With URTI Phase 3
Completed NCT01735084 - Using Pneumococcal Vaccines in Combination for Maximum Protection From Ear and Lung Infections in First 3 Years of Life Phase 4
Not yet recruiting NCT03461692 - A Registry Study of 100 Thousand Cases of Pediatric Patients on Reduning Injection（a Chinese Medicine Injection）Used in Hospitals in China N/A
Completed NCT03011515 - Evaluating a Host-response Based Diagnostic for Distinguishing Between Bacterial and Viral Etiology in Patients With Lower Respiratory Tract Infection (LRTI)