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Clinical Trial Summary

Caesarean section is one of the most common surgical procedures. The multiplication of uterine scars leads to an increase in complications and in particular those related to poor healing such as isthmocele or uterine rupture. The processes of uterine healing at the histological scale are little known. The main objective of the research is to analyze the process of uterine healing by means of uterine biopsies performed on the areas of cesarean section scars.


Clinical Trial Description

Our hypothesis is that there is a histological healing defect visible on an anatomopathologic examination of the scar. This poor uterine healing on histological scale is probably associated with uterine healing defects visible on pelvic ultrasound (scar dehiscence) and clinical criteria (number of caesareans, symptoms). The objective of the research is to analyze uterine scarring by means of uterine biopsies performed on the areas of cesarean section scars. The uterine scarred areas will be analyzed histologically according to specific criteria and compared to healthy uterine areas. Histological characteristics will be compared with clinical and ultrasound data. ;


Study Design


NCT number NCT05785559
Study type Interventional
Source Assistance Publique - Hôpitaux de Paris
Contact Perrine CAPMAS
Phone 0145217714
Email perrine.capmas@aphp.fr
Status Not yet recruiting
Phase N/A
Start date April 1, 2023
Completion date July 1, 2024