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Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced HNSCC

Squamous Cell Carcinoma of Head and Neck Clinical Trial

Official title:
Reducing Excision Margins After Neoadjuvant Chemoimmunotherapy for HPV Negative Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma (REMATCH)

Clinical Trial Summary

This study aims to explore the 2-year DFS (disease-free survival) rate and organ retention rate and to explore the ORR, PCR rate, 2y-OS， and quality of life of patients.

Clinical Trial Description

This study aims to explore the 2-year DFS (disease-free survival) rate and organ retention rate after AP chemotherapy combined with anti-PD-1 antibody neoadjuvant treatment for HPV negative operable locally advanced head and HNSCC, and to explore the ORR, PCR rate, 2y-OS, and quality of life of patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05459415
Study type Interventional
Source Wuhan Union Hospital, China
Contact
Status Active, not recruiting
Phase N/A
Start date June 22, 2022
Completion date June 21, 2027
View Details
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