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Clinical Trial Summary

This is a 2 stage multi-center study designed to evaluate the efficacy of the combination of alpelisib and fulvestrant in patients with PIK3CA-mutated ER-positive endometrioid endometrial cancers by estimating the objective response rate (ORR). Treatment will continue until either unacceptable toxicity, progression of disease, or investigator/patient request for withdrawal.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05154487
Study type Interventional
Source GOG Foundation
Contact Jennifer Klein, MEd
Phone 215-854-0770
Email jklein@gog.org
Status Recruiting
Phase Phase 2
Start date February 28, 2024
Completion date April 1, 2026