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Clinical Trial Summary

For patients with mild head trauma, a large number of CT scans are performed. The S100B protein allows, when the dosage is below the threshold, to rule out the diagnosis of brain damage with a negative predictive value of 98%. In patients over 65 years old it was found that the dosage of S100B came back positive more often compared to a younger population. This study proposes to determine the positivity threshold value for S100B dosage in patients over 65 years old. In patients over 65 years suffering from mild head trauma, a head CT will systematically be performed (in accordance with the recommendations) and the S100B will be measured (taken from an additional tube on the blood test carried out in these patients). The results of the TDM will then be compared with the results of the S100B to determine the values of sensitivity, specificity, negative and positive predictive value of different thresholds.


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT05091125
Study type Observational
Source University Hospital, Strasbourg, France
Contact Etienne QUOIRIN, Dr
Phone 03 88 12 86 52
Email etienne.quoirin@chru-strasbourg.fr
Status Not yet recruiting
Phase
Start date November 2, 2021
Completion date November 2, 2024