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Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of ES-SCLC

Extensive Stage Small Cell Lung Cancer Clinical Trial

Official title:
Clinical Study of Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of Extensive Stage Small Cell Lung Cancer

Clinical Trial Summary

The efficacy of PD-1/PD-L1 combined with chemotherapy in the treatment of extensive small-cell lung cancer is still unsatisfactory. PD-1/PD-L1 combined with chemotherapy and anti-angiogenic drugs may achieve better efficacy.

Clinical Trial Description

Camrelizumab is a humanized PD-1 monoclonal antibody. Camrelizumab combined with the antiangiogenic drug apatinib has achieved good efficacy in extensive small-cell lung cancer. Median OS is 8.4 months. In our study, subjects with extensive stage small cell lung cancers receive 2 cycles of chemotherapy followed by carrizumab combined with apatinib and chemotherapy. we hope to achieve a better outcome. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05001412
Study type Interventional
Source Guangzhou Institute of Respiratory Disease
Contact Chengzhi Zhou, MD
Phone 13560351186
Email doctorzcz@163.com
Status Recruiting
Phase Phase 1
Start date January 27, 2021
Completion date January 25, 2024
View Details
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