Anaesthetic Drugs, Hypotensive Drugs, Perioperative Analgesia Clinical Trial
Official title:
ERECTOR SPINAE PLANE BLOCK COMBINED WITH GENERAL ANAESTHESIA VERSUS CONVENTIONAL GENERAL ANAESTHESIA IN LUMBAR SPINE SURGERY
Ultrasound guided erector spinae plain block combined with general anaesthesia versus conventional general anaesthesia in lumbar spine surgery, it's hypothesized that combined regional anaesthesia with general anaesthesia in lumbar spine surgery may reduce the anaesthetic requirements, aid in controlled hypotension and improve the perioperative pain management.
Primary outcomes:
• Anaesthetic requirements: based on entropy monitoring(state and response entropy monitoring
and the difference as a measure for adequacy of analgesia) and haemodynamic parameters (
heart rate and mean arterial blood pressure) at the following time intervals: before
induction, after induction, after giving either ESP block or multimodal analgesia and
starting surgical stimulus, at 30 min intervals, at end of anaesthesia, at eye opening.
Secondary outcomes:
- Stress response measurement based on serum cortisol and blood glucose levels
- Controlled hypotensive anaesthesia: various drugs required and doses given
- Intraoperative and postoperative analgesia.
- Postanaesthesia care unit data concerning recovery.
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