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A Phase II Study of RBM-007 Alone and RBM-007 With Eylea® in Subjects With Wet Age-related Macular Degeneration — TOFU  

Exudative Age-related Macular Degeneration Clinical Trial

Official title:
A Multi-Center, Randomized, Double Masked and Active Controlled Phase II Study Assessing the Efficacy and Safety of Intravitreal Injections of RBM-007 Monotherapy and RBM-007 in Combination With Eylea® Compared to Eylea® Monotherapy

Clinical Trial Summary

This is a multicenter, active-controlled, double masked study assessing the safety, efficacy and durability of four monthly intravitreal (IVT) injections of RBM-007 monotherapy, and four monthly RBM-007 injections in combination with Eylea® dosed at every other month, compared to Eylea® monotherapy dosed at every other month in approximately eighty-one subjects with exudative age-related macular degeneration (AMD).

Clinical Trial Description

RBM-007 is a novel oligonucleotide-based aptamer having potent anti-FGF2 activity and anti-VEGF-expression activity ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04200248
Study type Interventional
Source Ribomic USA Inc
Contact
Status Completed
Phase Phase 2
Start date December 2, 2019
Completion date December 22, 2021
View Details
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