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Multiple Doses of DM199 in Patients With Chronic Kidney Disease (REDUX)

Kidney Diseases Clinical Trial

Official title:
A Multi-Center Open-label Investigation to Assess the Safety and Efficacy of Multiple Doses of DM199 in Patients With Chronic Kidney Disease

Clinical Trial Summary

An open-label, Phase II, multi-center study evaluating multiple doses of DM199 in participants with chronic kidney disease.

Clinical Trial Description

This is an open-label, Phase II, multi-center study evaluating DM199 in approximately 90 Participants in three cohorts. Cohort I: African Americans with CKD (Stage II or III), hypertension and non-diabetic Cohort II: Participants with IgA nephropathy diagnosis and CKD (Stage II or III) Cohort III: Diabetes Mellitus (Type II) with CKD (Stage II or III) and hypertension Participants in each cohort will be enrolled in a parallel assignment to one of two doses: Dose 1: DM199 2.0 µg/kg SC 2x week for 95 days Dose 2: DM199 5.0 µg/kg SC 2x week for 95 days ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04123613
Study type Interventional
Source DiaMedica Therapeutics Inc
Contact
Status Completed
Phase Phase 2
Start date December 17, 2019
Completion date March 16, 2022
View Details
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