Perioperative/Postoperative Complications Clinical Trial
Official title:
Evaluation of hsTnT for Perioperative Risk Stratification Among Patients Undergoing Elective Non-cardiac Surgery
Aim of this study is to evaluate whether the periopertive course is able to predict postoperative complications. Several approaches will be choosed to optimize perioperative risk stratification predicting postoperative complications in patients undergoing elective non-cardiac surgery.
The aim of this secondary analysis of the SUPERADD study is to use the perioperative data from the prospective SUPERADD study ("SUbstitution of PERioperative Albumin Deficiency Disorders") (Eudra-CT 2016-001313-24; Clinical Trials NCT03167645; DOI: 10.1097) to identify risk factors for the occurrence of postoperative complications, based on the Clavien-Dindo classification in the nine domains of the Postoperative Morbidity Survey. Multivariate Analyses, Decision trees, time series analysis and Machine Learning methods will be applied to distinguish risk factors for postoperative complikations and mortality in a high-risk group (see publication of the statistical analysis plan and its enhancement). Patients participating in the SUPERADD study (NCT03167656) and who had at least two perioperative high sensitive Troponin T (hsTnT) values in order to detect myocardial injury were included in this secondary analysis as hsTnT is associated with major adverse cardiovascular events (MACE), myocardial injury after noncardiac surgery and mortality. The secondary analysis uses data obtained at the pre-anaesthesia visit like ASA, preoperative comorbidities measured by the POSPOM, CCI, intraoperative parameters like vitals, medication, estimated blood loss and postoperative data obtained from PACU records and discharge letter. Primary Endpoint are postoperative complications assessed with the Cavien-Dindo classification > 2. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT03994419 -
PErioperAtive CHildhood ObesitY
|
||
| Active, not recruiting |
NCT01681238 -
Goal-directed Therapy in High-risk Surgery
|
N/A | |
| Recruiting |
NCT05613439 -
The Fast-track Centre for Hip and Knee Replacement Database
|
||
| Recruiting |
NCT03740438 -
Modeling of the Hemoglobin Drop in the Uncomplicated Postoperative Course
|
||
| Completed |
NCT03269760 -
Multimodal Sleep Pathway for Shoulder Arthroplasty
|
Phase 1 | |
| Recruiting |
NCT05594199 -
Feasibility of a Virtual Smoking Cessation Program
|
N/A | |
| Completed |
NCT00538499 -
Fentanyl With or Without Bupivacaine in Reducing Pain in Patients Undergoing Video-Assisted Chest Surgery
|
N/A | |
| Recruiting |
NCT01690338 -
A Study of Residual Curarization Incidence in China
|
Phase 4 | |
| Recruiting |
NCT01110798 -
J-Pouch Colorectal Anastomosis or Straight Colorectal Anastomosis in Treating Patients With Rectal Cancer Who Have Undergone Surgery to Remove the Tumor
|
N/A | |
| Completed |
NCT00859157 -
Pain After Tumescent Mastectomy or Standard Mastectomy in Women With Stage I, Stage II, or Stage III Breast Cancer
|
N/A | |
| Withdrawn |
NCT03531268 -
Prospective Study to Evaluate the Clinical Utility of Perioperative Pharmacogenomic Testing
|
N/A | |
| Recruiting |
NCT04356638 -
a Phase III Trial of Safety and Efficacy of Premedication With Dexmedetomidine and Midazolam in Pediatric Patients
|
Phase 3 | |
| Completed |
NCT03579121 -
Genomic Opioid Optimization of Dosing and Selections (GOODS) Study
|
N/A | |
| Completed |
NCT03899441 -
Multimedia Aid Gynecologic Counseling and Consent
|
N/A | |
| Recruiting |
NCT06123039 -
Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
|
||
| Completed |
NCT01672892 -
Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer
|
Phase 3 | |
| Completed |
NCT01510652 -
More Options Available With a Quadripolar LV Lead pRovidE In-clinic Solutions to CRT Challenges
|
N/A | |
| Completed |
NCT01680367 -
Wound Dressings For Split-Thickness Skin Graft Donor Sites in Patients Undergoing Surgery
|
N/A | |
| Active, not recruiting |
NCT00005600 -
Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer
|
N/A | |
| Recruiting |
NCT05743673 -
SHAPE Test for Preoperative Risk Stratification
|