Mechanisms of Alcohol Sensitivity in AERD

Aspirin-Sensitive Asthma With Nasal Polyps Clinical Trial

Official title:
Mechanisms of Alcohol Sensitivity in Aspirin Exacerbated Respiratory Disease

Status Recruiting

Clinical Trial Summary

The purpose of this study is to determine what type of reactions in the body may be responsible for the respiratory symptoms that occur when patients with Aspirin Exacerbated Respiratory Disease (AERD) drink alcoholic beverages. These reactions are most often seen with red wine.

Clinical Trial Description

This is a prospective trial of approximately 60 subjects with AERD to explore the mechanisms behind the physiologic reactions that occur when drinking alcoholic beverages. At various time points patients will be asked to ingest a variety of substances found in red wine after which blood and urine markers of the reaction will be measured. ;

Study Design

Related Conditions & MeSH terms

Aspirin-Sensitive Asthma With Nasal Polyps
Hypersensitivity
Nasal Polyps
Samter's Syndrome

Clinical Trial Details

NCT number	NCT03441438
Study type	Interventional
Source	University of Virginia
Contact	BJ Ferrebee-Ghamandi, MHA
Phone	434-243-1558
Email	Bjf8j@hscmail.mcc.virginia.edu
Status	Recruiting
Phase	N/A
Start date	May 1, 2018
Completion date	September 1, 2018

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT03973749` - Effects of a High or Low Salycilate Diet on Urinary LTE4 and Clinical Features in AERD	N/A
Withdrawn	`NCT01615536` - The Role of Canine Fossa Trephination in the Severely Diseased Maxillary Sinus	N/A
Recruiting	`NCT05575037` - Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease	Phase 2
Completed	`NCT03326063` - Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban	Phase 2