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Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury — BRICK  

Contrast-induced Acute Kidney Injury Clinical Trial

Official title:
Biochemical and Reno-protective Effects of Remote Ischemic Pre-conditioning on Contrast-induced Acute Kidney Injury

Clinical Trial Summary

This a prospective, double-blind, sham-controlled, randomized clinical trial to study the effects of remote ischemic preconditioning on contrast-induced acute kidney injury, vascular and renal biomarkers in patients with non-ST elevation myocardial infarction and unstable angina undergoing cardiac catheterization and percutaneous coronary intervention.

Clinical Trial Description

The BRICK study is a prospective, double-blind, sham-controlled, randomized clinical trial in patients with non-ST elevation myocardial infarction and unstable angina undergoing cardiac catheterization and percutaneous coronary intervention who are at high risk for contrast-induced acute kidney injury. The study will investigate the effects of remote ischemic preconditioning before cardiac catheterization on rate of contrast induced acute kidney injury and novel biomarkers of renal injury/protection within 48hrs of cardiac catheterization. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03236441
Study type Interventional
Source University of Pittsburgh
Contact
Status Active, not recruiting
Phase N/A
Start date March 6, 2018
Completion date February 28, 2024
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