Refractory Hepatic Encephalopathy Clinical Trial
Official title:
High Volume Plasmapheresis for Refractory Hepatic Encephalopathy in Liver Intensive Care Unit-A Randomized Controlled Trial
Study Design- Randomized Controlled trial Duration of enrolment-Feb-2016 to December 2017
Sample size-120 patients Methodology We will include consecutive with advanced hepatic
encephalopathy not responding to treatment of precipitants and on treatment with Lactulose
and Rifaximin for 48 hours .
Two groups will be divided. One arm -Lactulose and Rifaximin will be continued Second Arm -
Plasmapheresis will be added to the standard medical care therapy.(Maximum of 3 sessions once
in 24 hours/or alternate days with an follow up for 5 days)
n/a