Quantification of Autonomic Nervous Activity During Hemodialysis

Chronic Kidney Disease on Hemodialysis Clinical Trial

Official title: Quantification of Autonomic Nervous Activity by Heart Rate Variability and Approximate Entropy in High Ultrafiltration Rate During Hemodialysis

Status Completed

Clinical Trial Summary

This study assesses autonomic nervous system function by power spectral analysis of RR interval dynamics in ultrafiltration subjects without blood pressure variation.

Clinical Trial Description

Variations over time in autonomic nervous activity due to differences in ultrafiltration rate will be evaluated by measuring heart rate variability in hemodialysis patients without blood pressure variations during HD session.

The subjects will be divided into 3 groups, those with UFR < 10 ml/hr/kg; ≥10 ml/hr/kg but ≤ 15 ml/hr/kg; and >15 ml/hr/kg, and Holter ECG are recorded continuously during HD session using frequency analysis of RR intervals. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Chronic Kidney Disease on Hemodialysis
• Kidney Diseases
• Renal Insufficiency, Chronic

• NCT number: NCT02754986
• Study type: Interventional
• Source: University of Hyogo
• Status: Completed
• Phase: N/A
• Start date: March 2015