Health Knowledge, Attitudes, Practice Clinical Trial
Official title:
Two Alternatives Versus Usual GRADE-SoF Tables to Improve Understanding in the Presentation of Systematic Review Results: a Three-arm Randomized Controlled Trial
Background: Summary of Findings (SoF) tables have been developed to present results of
systematic reviews in a concise and explicit format. Adopted by many review groups including
the Cochrane Collaboration, the Agency for Healthcare Research and Quality (AHRQ), and the
GRADE Working Group; SoF tables provide succinct, transparent, and easily interpretable
judgments about the certainty of evidence and magnitude of effects. Currently, there are
three different SoF formats in use. This study aims to compare SoF table formats in terms of
understanding, accessibility, satisfaction, and preference with systematic review users.
Methods: The primary objective of this three-arm randomized control non-inferiority trial is
to investigate the understanding of information presented in three different SoF tables: a
new current GRADE-SoF table, a new alternative GRADE-SoF table, and EPC-SoF table with
systematic review users. Researchers, clinical practice guideline developers, policy-makers,
end-users, or knowledge transfer will be recruited. Data will be collected electronically at
baseline and after randomization.
Discussion: This study aims to assess the understanding, accessibility, satisfaction, and
preference between three SoF tables for displaying summary evidence from health-related
outcomes. The results of this study will provide important knowledge to understand what
information should be included in SoF tables in systematic reviews.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Health Services Research
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