Detecting Abnormal Fetal Karyotype by the Electronic Nose Clinical Trial
Official title:
Examining the Ability of Electronic Nose in Detecting Fetal Chromosomal Disorders
"electronic nose"- the tiny sensors, will smell and detect the changes in the sample of abnormal fetal karyotype, and fluid that will be confirmed by amniocentesis.
The biochemical engineering department had developed a device called "electronic nose" that
can detect various diseases Including cancer and asthma on basis of evaporable substances.
The device simulates the human nose ", which includes an array of tiny sensors connected to
nanometric sizes electronic calculating unit.. Thanks to their small size, electrical,
physical and chemical properties, the sensitive sensors smell and identified changes in
composition of the materials that characterize various diseases including kidney disease and
asthma.
The electronic nose was developed by Professor Haick from the Technion. The main concept of
the device is testing and characterization a trace amounts of substances in the air with the
help of nana-technology sensors the idea is revolutionary and would allow the diagnosis of
different diseases, like cancer, by exhaling air into the device.
The test is simple and not complicated to perform ,the examiner inhale air into a bag which
connected to the "electronic nose". The molecules of the patient's breath will be tied to
sensors and transmit an electrical signal to computer chip.
After processing the data the "electronic nose "can distinguish between normal cells and
pathological cells.
Hypothesis: the tiny sensors ("electronic nose") will smell and detect the changes in the
sample of abnormal fetal karyotype, and fluid that will be confirmed by amniocentesis.
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Observational Model: Case Control, Time Perspective: Prospective