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Clinical Trial Summary

Delirium, an acute change in mental status, is a serious medical complication among hospitalized patients. Syndrome of delirium involves agitation, sleep disturbance, affective disorders and cognitive disruptions.

One vulnerable period for developing delirium is in the postoperative days. Postoperative delirium often initiates a cascade of adverse consequences including an increase in length of stay and hospital costs, and greater mortality. The investigators have observed that the incidence of postoperative delirium in patients after renal transplantation is about 20-30% in our hospital.

Several studies have revealed that dexmedetomidine, as a widely used sedative during anesthesia, can decrease the incidence of postoperative delirium after cardiac surgery. The investigators aim to examine whether administration of dexmedetomidine can reduce postoperative delirium after living donor renal transplantation in adult patients.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Delirium
  • Postoperative Delirium After Living Donor Renal Transplantation

NCT number NCT02509949
Study type Interventional
Source First Affiliated Hospital, Sun Yat-Sen University
Contact
Status Recruiting
Phase Phase 4
Start date May 2015