Postoperative Delirium After Living Donor Renal Transplantation Clinical Trial
Delirium, an acute change in mental status, is a serious medical complication among
hospitalized patients. Syndrome of delirium involves agitation, sleep disturbance, affective
disorders and cognitive disruptions.
One vulnerable period for developing delirium is in the postoperative days. Postoperative
delirium often initiates a cascade of adverse consequences including an increase in length of
stay and hospital costs, and greater mortality. The investigators have observed that the
incidence of postoperative delirium in patients after renal transplantation is about 20-30%
in our hospital.
Several studies have revealed that dexmedetomidine, as a widely used sedative during
anesthesia, can decrease the incidence of postoperative delirium after cardiac surgery. The
investigators aim to examine whether administration of dexmedetomidine can reduce
postoperative delirium after living donor renal transplantation in adult patients.
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