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Clinical Trial Summary

A pilot phase II study with brentuximab vedotin as pre-ASCT induction therapy in relapsed/refractory Hodgkin's lymphoma patients non-responding to IGEV salvage treatment.


Clinical Trial Description

Brentuximab vedotin emerged as active single-agent in the treatment of relapsed or refractory HL.

Some patients don't reach a complete response after salvage treatment with IGEV (ifosfamide, gemcitabine, vinorelbine) and remain PET positive so the idea is to treat this subset of patients with brentuximab vedotin with the aim of achieving a complete remission before transplant. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02244021
Study type Interventional
Source Fondazione Italiana Linfomi ONLUS
Contact
Status Completed
Phase Phase 2
Start date December 2014
Completion date October 2017