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Clinical Trial Summary

The purpose of the study is to determine the clinical safety and operability of the innovative tissue imprint device ProTool.


Clinical Trial Description

Current limitations in the management of high grade brain tumors partly reside in the lack of access to pathological tissue.

Conventional biopsy devices can cause severe side effects, thus limiting the amount of tissue that can be collected for molecular characterization. The Brain-Tissue-Imprint Devices evaluated in this trial offers a unique opportunity to perform multiple non-lesion sampling in both tumor tissue and peritumoral areas. The approach relies on the use of tailored silicon chips integrated in surgical devices enabling tissue sampling through a brief "silicon to tissue contact", thus limiting potential side effects, and opening a way to extensive molecular investigation of brain tumors and their microenvironment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02077543
Study type Interventional
Source University Hospital, Grenoble
Contact François BERGER, MD, PhD
Email francois.berger@inserm.fr
Status Recruiting
Phase Early Phase 1
Start date October 2013
Completion date December 2020