Post Cardiac Arrest Patient Who Was Treated by Hypothermia Protocol Clinical Trial
Postresuscitation disease is a constellation of disorders related to whole-body ischemia and
reperfusion syndrome. It includes hypoxic damage in brain, liver, kidney, heart and other
organ. In previous study more than one-third of patients resuscitation from out of hospital
cardiac arrest developed renal dysfunction. In acute kidney injury, NGAL is an earlier
marker compared with serum creatinine.
Cardiac arrest and severe asphyxia result in global brain ischemia. In previous study serum
NGAL correlated with hypoxic ischemic encephalopathy in asphyxiated neonate.
This study was designed to assess serum NGAL level in postresuscitative patients to evaluate
its relation to hypoxic brain injury severity, and its clinical utility for early detection
of acute kidney injury in these patients.
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Observational Model: Cohort, Time Perspective: Prospective