Non-squamous Cell Non-Metastatic Non-Small Cell Lung Cancer Clinical Trial
Official title:
Neoadjuvant Chemotherapy for Non-metastatic Non-small Cell Lung Cancer
To determine the rate of pathologic complete responses (pCR) at the time of definitive surgical resection of non-small cell lung cancer (NSCLC)
Participants in this study will have a lung mass and are undergoing a procedure to determine
if they have non-small cell lung cancer that could be removed surgically. If confirmed to
have non-small cell lung cancer that can be surgically removed, he or she may be able to
continue as a possible participant in this study.
The purpose of this study is to determine whether neoadjuvant chemotherapy (chemotherapy that
is given before surgery) will improve the amount of time a participant is free from disease
in people with non-metastatic (has not spread from the original site) non-small cell lung
cancer. The chemotherapy medications that will be used in this study are cisplatin and
pemetrexed or cisplatin and gemcitabine and have been shown to be effective in patients with
non-small cell lung cancer.
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