ALLPS VERSUS PVO Randomized Controlled Trial — ALPPS  

Liver Tumors Not Resectable in One Surgical Procedure Clinical Trial

Official title: ASSOCIATING LIVER PARTITION WITH PORTAL VEIN LIGATION FOR STAGED HEPATECTOMY (ALPPS) Versus Conventional Portal Vein Occlusion (PVO) for Resection of Liver Tumors Unresectable in One Step - a Randomized Controlled Trial

Status Terminated

Clinical Trial Summary

This randomized phase II trial compares how well associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) or portal vein occlusion (PVO) works in treating patients with liver cancer. Both treatments are types of 2-stage hepatectomies for removing liver cancer. ALPPS may be more effective than PVO in patients whose disease would traditionally be considered inoperable.

• Trial with surgical intervention

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Liver Neoplasms
• Liver Tumors Not Resectable in One Surgical Procedure

• NCT number: NCT01775267
• Study type: Interventional
• Source: University of Zurich
• Status: Terminated
• Phase: Phase 2
• Start date: November 2012
• Completion date: November 2015