End-stage Renal Disease Clinical Trial
Official title:
Improving of Morphological,Clinical Biochemical and Instrumental Functional Reserve Estimation of Donor Kidney
The purpose of the study:
- To estimate the role of morphological, clinical, biochemical and imaging studies at
stages of kidney transplantation (medical therapy, explantation, preservation,
transplantation).
- To improve the ways of preserving optimal functional parameters of renal transplants.
Terminal chronic renal failure (ESRD) as a result of almost any chronic kidney disease
develops due to progressive loss of nephrons. This state is characterized by a gradual
deterioration of the functional abilities of not only the kidneys, but also the whole body.
Currently, ESRD is among the first ten causes of mortality .
Transplantation of donor organs is the only radical treatment for various diseases of the
terminal, for patients with a fatal prognosis.
Kidney transplantation has allowed not only save lives, but also to return to normal life,
tens of thousands of people. Survival of renal transplant recipients is growing.
Despite the progress made in many clinics worldwide in recent years in the field of
transplantation, kidney transplantation, does not settle the problem of reperfusion injury
and the associated post-transplant dysfunction with the absence of clear indicators of
morphological, clinical, biochemical and instrumental methods to assess functional reserve
of organs that remain relevant and meaningful.
;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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