Descemet's Stripping Endothelial Keratoplasty Clinical Trial
Official title:
Investigation of Treatment With Topical Corticosteroid After Posterior Lamellar Corneal Transplantation
After corneal transplantation, topical corticosteroids are used to reduce the risk of
rejection.
However, the optimal postoperative treatment regimen is unknown. In most cases, a topical
steroid is administered for at least 6 months after surgery, but it remains to be determined
whether potent steroids offer better protection than weak steroids. Also, the length of the
treatment is debated.
Since the use of steroids is not without potential serious ocular side effects, it is of
considerable importance to investigate these problems.
The study aims to examine the frequency of rejection episodes after posterior lamellar
keratoplasty; specifically comparing a short course of potent steroids versus a long course
of weak steroids.
n/a
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment