Aneurysmal Subarachnoid Hemorrhage Clinical Trial
Official title:
Ultrasound Perfusion Imaging After Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to examine wether delayed cerebral ischemia can be predicted by ultrasound brain perfusion imaging in patients with aneurysmal subarachnoid hemorrhage (SAH).
The delayed cerebral ischemia is a main complication in patient with aneurysmal subarachnoid
hemorrhage which causes neurological deficit. So far there is no reliable diagnostic tool to
predict the appearance of cerebral ischemia.
The causal correlation between presence of cerebral vasospasm measured daily by transcranial
Doppler sonography (TCD) and occurrence of cerebral ischemia detected by cranial computed
tomography scan (CCT) is not finally verified.
First studies demonstrated that ultrasound perfusion imaging (UPI) allows the detection of
perfusion deficits in middle cerebral artery infarction.
The purpose of our study is to evaluate the diagnostic and prognostic value of UPI to
predict delayed cerebral ischemia. In our trial we compare parameters of UPI (b= rise rate,
A= plateau of acoustic intensity) in patients with aneurysmal subarachnoid hemorrhage with
results of follow-up cranial computed tomography scans (CCT), TCD results and clinical
outcome.
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Observational Model: Case-Only, Time Perspective: Prospective
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