Biomarkers in Samples From Younger Patients With Wilms Tumor

Wilms Tumor and Other Childhood Kidney Tumors Clinical Trial

Official title: Observational - Relationships Between Tumor-Associated Macrophages and Clinicopathological Factors in Wilms Tumor

Status Completed

Clinical Trial Summary

This research study is studying biomarkers in tissue samples from younger patients with Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment

Clinical Trial Description

PRIMARY OBJECTIVES:

I. To determine whether recruitment of tumor-associated macrophages is related to clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion, tumor progression, and survival).

OUTLINE:

Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample are then compared with patient's tumor stage, presence of vascular invasion, tumor progression, and survival. ;

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Kidney Neoplasms
• Wilms Tumor
• Wilms Tumor and Other Childhood Kidney Tumors

• NCT number: NCT01493817
• Study type: Observational
• Source: Children's Oncology Group
• Status: Completed
• Phase: N/A
• Start date: December 2011