Candidemia Prognostic Factor and Mycobiological Analysis. Clinical Trial
Official title:
The Relationship Between Morphology and Virulent Genes of Candida Albicans and Clinical Aspects, Surveillance of Fungemia
Candida albicans is the most common and important clinical fungal pathogen. Our previous
surveillance disclosed that fluconazole could induce different morphological changes in
clinical strains. Our current study on C. albicans causing candiuria disclosed that renal
insufficiency , diabetes mellitus, respiratory failure and uremia were risk factors of
treatment failure. However, we also found results of E-test drug susceptible test could not
predict outcome. Hence, retrospective analysis of 31 months period, cases that had C.
albicans inducing candidemia were reviewed and 60 cases were enrolled for morphological
study and potential virulent gene analysis.
This study is designed to clarity the clinical meaning of morphological form and virulent
genes on candidemia. To do this study is probably helpful for treatment of candidiasis.
n/a
Observational Model: Case-Only, Time Perspective: Retrospective