Adhesion of Flexor Tendon of Hand Clinical Trial
Official title:
Study of Collagenase Injection Therapy for Treatment of Zone II Flexor Tendon Adhesions in the Hand
The purpose of this study is to dissolve flexor tendon adhesions associated with failed tendon repair surgery.
In an open label study, collagenase injection therapy was investigated in 3 subjects for
it's ability to lyse flexor tendon adhesions in zone II of the hand.
Results indicate that two of three subjects had improved range of finger motion at the PIP
and DIP joints. This may obviate the need for patients to have tenolysis hand surgery to
correct the finger flexion contracture of the PIP and DIP joints. Detailed controlled
studies remain to be done.
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Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment